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Larvicidal,Aedes aegypti mosquito.xp Parasitol

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

6

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0381
    Maackiain

    DL-​Maackiain

    		 Parasite Apoptosis Infection
    Maackiain (DL-Maackiain) is isolated from Maackia amurensis Rupr.et Maxim. Maackiain (DL-Maackiain) is a larvicidal agent against Aedes aegypti mosquito.xp Parasitol with a LD50 of  21.95 µg/mL . Maackiain (DL-Maackiain) induces fragmentations of DNA to oligonucleosomal-sized fragments that like a characteristic of apoptosis in the HL-60 cells .
    Maackiain
  • HY-116934
    5-Pentadecylresorcinol
    1 Publications Verification

    Adipostatin A

    		 Others Infection Cancer
    5-Pentadecylresorcinol (Adipostatin A) is a glycerol-3-phosphate dehydrogenase (GPDH) inhibitor with an IC50 of 4.1 µM. Adipostatin A shows good larvicidal activity against Aedes aegypti .
    5-Pentadecylresorcinol
  • HY-N9842
    Violanone

    		Microtubule/Tubulin Infection
    Violanone, an isoflavanone compound, can inhibit tubulin polymerization. Violanone also exhibits larvicidal activity against A. aegypti .
    Violanone
  • HY-N2976
    Cabraleadiol monoacetate

    Betulafolianediol 3-acetate; Cabraleadiol 3-acetate

    		 Others Infection
    Cabraleadiol monoacetate is a compound isolated from the lichen Pyxine consocians Vainio. Cabraleadiol monoacetate shows mosquito larvicidal activity against the second instar larvae of Aedes aegypti .
    Cabraleadiol monoacetate
  • HY-N8914
    Isoshinanolone

    		Others Others
    Isoshinanolone is a natural product that can be extracted from Plumbago capensis. Isoshinanolone has mosquito larvicidal activity against fourth instar larvae of A. aegypti, with an IC50 value of 1.26 μg/mL .
    Isoshinanolone
  • HY-N1739
    Tectoquinone

    2-Methylanthraquinone
    Tectoquinone (2-Methylanthraquinone) is a SARSCoV-2 main protease inhibitor against COVID-19. Tectoquinone exhibits strong mosquito larvicidal activity with the LC50 values of 3.3 and 5.4 μg/ml against A. aegypti and A. albopictus in 24 h, respectively .
    Tectoquinone
  • HY-118607
    VU041

    		Potassium Channel Parasite Infection
    VU041 is a first submicromolar-affinity inhibitor of Anopheles (An.) gambiae and Aedes (Ae.) aegypti inward rectifier potassium 1 (Kir1) channels with IC50 values of 2.5 μM and 1.7 μM, respectively. VU041 inhibits appreciably is mammalian Kir2.1 (IC50 of 12.7 μM), and has less inhibitory effect on mammalian Kir1.1, Kir4.1, Kir6.2/SUR1, and Kir7.1. VU041 also induces impaired Malpighian tubule function .
    VU041
  • HY-134891
    HMBPP

    (E)-4-Hydroxy-3-methyl-but-2-enyl diphosphate

    		 Nuclear Factor of activated T Cells (NFAT) Infection Inflammation/Immunology
    HMBPP (E-4-Hydroxy-3-methyl-but-2-enyl diphosphate) is an activator for human Vγ9/Vδ2 T cells. HMBPP exhibits phagostimulant property in mosquitos .
    HMBPP

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